Every year, Federal agencies with extramural research and development (R&D) budgets that exceed $100 Million are required to allocate a percentage (2.9 percent) FY15 of their R&D budget to these (SBIR) programs. Currently the following agencies participate in the program:

Department of Agriculture
Department of Commerce National Institute of Standards and Technology
Department of Commerce National Oceanic and Atmospheric Administration
Department of Defense
Department of Education
Department of Energy
Department of Health and Human Services
Department of Homeland Security
Department of Transportation
Environmental Protection Agency
National Aeronautics and Space Administration
National Science Foundation

Source: www.SBIR.Gov